• Review|Open Access

    Human leukocyte antigens-immunogenetics of neuromyelitis optica or Devic's disease and the impact on the immunopathogenesis, diagnosis and treatment: a critical review

    Maria Panos Gontika , Maria Constantinos Anagnostouli
    Neuromyelitis optica (NMO) is an autoimmune demyelinating disorder, predominantly characterized by severe optic neuritis, transverse myelitis and the high level of antibodies against aquaporin-4 (AQP4) or NMO-immunoglobulin G (IgG). Researches trying to correlate NMO with specific human leukocyte... Read more
    Neuroimmunol Neuroinflammation 2014;1:44-50. | doi:10.4103/2347-8659.139713
    Published on: 28 Aug 2014  | Viewed:9688  | Downloaded:221
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  • Review|Open Access

    Targeting glioma stem cells via the Hedgehog signaling pathway

    Yang Liu , Xing Liu , Ling-Chao Chen , Wen-Zhong Du , Yu-Qiong Cui , Xing-Yin Piao , Yong-Li Li , Chuan-Lu Jiang
    Cancer is one of the leading causes of death worldwide. Gliomas are among the most devastating tumor types, and current clinical therapies are unsatisfactory. Recent reports revealed the importance of glioma-propagating cells in the malignancy of gliomas. These cells, also referred to as glioma... Read more
    Neuroimmunol Neuroinflammation 2014;1:51-9. | doi:10.4103/2347-8659.139715
    Published on: 28 Aug 2014  | Viewed:23035  | Downloaded:309
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  • Review|Open Access

    Pyroptosis and neurological diseases

    Zhen Xie , Gang Zhao
    Pyroptosis is a new process of programmed cell death, which has been discovered and confirmed in recent years. Its cardinal features include activation of caspase-1 and a massive release of inflammatory cytokines (interleukin (IL)-1β, IL-18), etc. The morphological characteristics, occurrence and... Read more
    Neuroimmunol Neuroinflammation 2014;1:60-5. | doi:10.4103/2347-8659.139716
    Published on: 28 Aug 2014  | Viewed:7650  | Downloaded:457
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  • Review|Open Access

    Chronic inflammation drives glioma growth: cellular and molecular factors responsible for an immunosuppressive microenvironment

    Edward T. Ha , Joseph P. Antonios , Horacio Soto , Robert M. Prins , Isaac Yang , Noriyuki Kasahara , Linda M. Liau , Carol A. Kruse
    This review examines glioma disease initiation, promotion, and progression with a focus on the cell types present within the tumor mass and the molecules responsible for the immunosuppressive microenvironment that are present at each step of the disease. The cell types and molecules present also... Read more
    Neuroimmunol Neuroinflammation 2014;1:66-76. | doi:10.4103/2347-8659.139717
    Published on: 28 Aug 2014  | Viewed:13389  | Downloaded:641
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  • Original Article|Open Access

    Effect of conduction block in classification and prognosis of Guillain-Barre syndrome

    Yu-Chen Wang , Guo-Dong Feng , Jing Wang , Xue-Dong Liu , Gang Zhao
    Aim: The aim was to investigate the electro-physiological characteristics in disease progression of Guillain-Barre syndrome (GBS) and observe the effect of conduction block (CB) in classification and severity of the disease. Methods: Two hundred and ninety-four patients with GBS were divided into... Read more
    Neuroimmunol Neuroinflammation 2014;1:77-81. | doi:10.4103/2347-8659.139718
    Published on: 28 Aug 2014  | Viewed:9966  | Downloaded:231
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  • Original Article|Open Access

    A novel method for evaluating microglial activation using ionized calcium-binding adaptor protein-1 staining: cell body to cell size ratio

    Iris Bertha Hovens , Csaba Nyakas , Regien Geertruida Schoemaker
    Aim: The aim was to validate a newly developed methodology of semi-automatic image analysis to analyze microglial morphology as marker for microglial activation in ionized calcium-binding adaptor protein-1 (IBA-1) stained brain sections. Methods: The novel method was compared to currently used... Read more
    Neuroimmunol Neuroinflammation 2014;1:82-8. | doi:10.4103/2347-8659.139719
    Published on: 28 Aug 2014  | Viewed:18902  | Downloaded:738
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  • Case Report|Open Access

    Posterior reversible encephalopathy syndrome due to seronegative systemic lupus erythematosus

    Sawan Verma , Irfan Yousuf , Mushtaq Ahmad Wani , Ravouf Asimi , Sheikh Saleem , Mudasir Mushtaq , Irfan Shah , Skeikh Nawaz , Riyaz Ahmad Daga
    Posterior reversible encephalopathy syndrome (PRES) is a neurotoxic state coupled with a unique computed tomography or magnetic resonance imaging (MRI) appearance. Recognized in the setting of a number of complex conditions (preeclampsia/eclampsia, allogeneic bone marrow transplantation, organ... Read more
    Neuroimmunol Neuroinflammation 2014;1:89-91. | doi:10.4103/2347-8659.139720
    Published on: 28 Aug 2014  | Viewed:6843  | Downloaded:157
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  • Case Report|Open Access

    Toluene-induced leukoencephalopathy with characteristic magnetic resonance imaging findings

    Fan Zeng , Heng Yang , Hua-Dong Zhou , Yan-Jiang Wang
    Toluene-induced leukoencephalopathy is a frequently seen medical condition worldwide; however the lack of specific clinical manifestations and laboratory tests makes it difficult to diagnose. Neuroimaging and medical history are often crucial to diagnosis of this disorder. In this report, a case... Read more
    Neuroimmunol Neuroinflammation 2014;1:92-4. | doi:10.4103/2347-8659.139721
    Published on: 28 Aug 2014  | Viewed:6601  | Downloaded:652
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  • Case Report|Open Access

    Malignant middle-cerebral artery territory infarction in tuberculous vasculitis

    Salvadeeswaran Meenakshi-Sundaram , Sundararajan Srinivasan , Somalinga Nagendran Karthik , Suresh Pandi , Alagappan Periyakaruppan , Bharathi Sundar
    Intracranial large vessel involvement is an unusual complication of tuberculous meningitis. The authors report a 39-year-old female presenting with an episode of seizure, followed by rapid decline in sensorium without prominent systemic features. An initial cranial magnetic resonance imaging... Read more
    Neuroimmunol Neuroinflammation 2014;1:95-7. | doi:10.4103/2347-8659.139722
    Published on: 28 Aug 2014  | Viewed:7348  | Downloaded:165
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  • Case Report|Open Access

    Primary diffuse large B-cell non-Hodgkin lymphoma of the cranial vault

    Shantanu Ghosh , Debabrata Das , Praveen Kumar , Rahul Varshney
    Primary non-Hodgkin lymphoma of the cranial vault with extra and intracranial extension in a nonimmunocompromised patient is extremely uncommon. Until date, only limited number of such cases has been reported in the literature and none was the lesion located as a diffuse swelling in the forehead.... Read more
    Neuroimmunol Neuroinflammation 2014;1:98-101. | doi:10.4103/2347-8659.139723
    Published on: 28 Aug 2014  | Viewed:7521  | Downloaded:139
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Neuroimmunology and Neuroinflammation Print ISSN: 2347-8659; Online ISSN: 2349-6142
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