Topic: Neurovascular and neuroinflammation mechanisms associated with bipolar disorder
Neuroinflammation has been proposed as a strong biological factor underlying the development of neuropsychiatric diseases. A role for dysregulation of the immune system was initially suggested in depressive disorders and subsequently extended to other illnesses, including bipolar disorder (BD). Indeed, there is growing evidence confirming the presence of a generalized pro‑inflammatory state in BD patients, involving alterations in cytokine, acute‑phase proteins, and complement factor secretion, white blood cell differentiation, microglial activation, arachidonic acid signaling pathways, and...
Published on: 15 Oct 2015