Topic: Alzheimer’s Disease

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A special issue of Neuroimmunology and Neuroinflammation  (Print ISSN:2347-8659; Online ISSN:2349-6142).

Deadline for manuscript submissions: 31 Mar 2018

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Guest Editor(s)

  • Dr. Raymond Chuen-Chung Chang, PhD
    Laboratory of Neurodegenerative Diseases, Department of Anatomy, LKS Faculty of Medicine, The University of Hong Kong, Laboratory Block, Faculty of Medicine Building, Pokfulam, Hong Kong, China.

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Submission Information:

For Author Instructions, please refer to http://nnjournal.net/pages/view/author_instructions
For Online Submission, please login at http://www.editorialmanager.com/neurimm/default.aspx
Submission Deadline: 31 Mar 2018
Contacts: Ruirui Zhang, Managing Editor, editor001@nnjournal.net

Published Articles Download All Articles
  • Altered filamin A enables amyloid beta-induced tau hyperphosphorylation and neuroinflammation in Alzheimer’s disease

    Lindsay H. Burns , Hoau-Yan Wang
    Alzheimer’s disease (AD) is a neurodegenerative disease with proteopathy characterized by abnormalities in amyloid beta (Aβ) and tau proteins. Defective amyloid and tau propagate and aggregate, leading to eventual amyloid plaques and neurofibrillary tangles. New data show that a third proteopathy, an altered conformation of the scaffolding protein filamin A (FLNA), is critically linked to the amyloid and tau pathologies in AD. Altered FLNA is pervasive in AD brain and without apparent aggregation. In a striking interdependence, altered FLNA is both induced by Aβ and required for two... Read more
    Neuroimmunol Neuroinflammation 2017;4:263-71. | doi:10.20517/2347-8659.2017.50
    Published on: 8 Dec 2017  | Viewed:2821  | Downloaded:93
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Neuroimmunology and Neuroinflammation ISSN 2349-6142 (Online), ISSN 2347-8659 (Print)
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