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Topic: Neuroinflammation in Alzheimer's Disease

A special issue of Neuroimmunology and Neuroinflammation

ISSN 2349-6142 (Online), ISSN 2347-8659 (Print)

Submission deadline: 31 Jul 2020

Guest Editor(s)

  • Dr. Daniele Orsucci, MD
    Unit of Neurology, San Luca Hospital, Lucca 55100, Italy.

    E-mail

Special Issue Introduction

The pathogenesis of Alzheimer's disease (AD) is complex, and only a minority of cases appears to be primarily genetic. A relationship between genetic and acquired factors in AD has been hypothesized. Many vascular risk factors for AD could result in cerebrovascular dysfunction. Oxidative damage and mitochondrial dysfunction have been also implicated in the pathogenesis of AD, but the question as to whether they are involved in the onset and progression of the pathology or rather represent a consequence of neurodegeneration is still debated. Recent evidence suggests that an abnormal inflammatory response may have a pivotal role. This special issue discusses the role of neuroinflammation in AD, focusing on the mechanisms that lead to vascular dysfunction, mitochondrial dysfunction, oxidative stress and neurodegeneration, a "vicious circle" that ends in dementia.

Keywords

Alzheimer, Alzheimer's disease, inflammation, neurodegeneration, neuroinflammation

Submission Deadline

31 Jul 2020

Submission Information

For Author Instructions, please refer to http://nnjournal.net/pages/view/author_instructions
For Online Submission, please login at https://oaemesas.com/nn
Submission Deadline: 31 Jul 2020
Contacts: Iris Marshall, Managing Editor, managingeditor@nnjournal.net

Published Articles

This special issue is now open for submission.