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    Case Report| Open Access

    Cerebral fat embolism syndrome after long bone fracture due to traffic accident: a case report

    Xing-Yong Chen, Jian-Ming Fan, Ming-Feng Deng, Ting Jiang, Feng Luo

    Cerebral fat embolism syndrome (CFES) is an uncommon but serious complication of long bone fracture. We reported a 19-year-old male patient who sustained CFES due to multiple limbs long bone fractures after a traffic accident injury. He gradually developed into coma within 24 h after his injury.... Read more

    Neuroimmunol Neuroinflammation 2018;5:31. | doi:10.20517/2347-8659.2018.23
    Published on: 1 Aug 2018  | Viewed:115  | Downloaded:10
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    Review| Open Access

    Therapeutic approach targeting apolipoprotein E binding region and low-density lipoprotein receptor for Alzheimer’s disease

    Michael Leon, Darrell Sawmiller, Brian Giunta, Jun Tan

    Approximately 13% of the population over the age of 65 years is estimated to have AD. The total number of cases is expected to increase over the coming decades. The apolipoprotein E (ApoE) genotype is the greatest genetic determinant for Alzheimer’s disease (AD) development. The ApoE4 allele... Read more

    Neuroimmunol Neuroinflammation 2018;5:30. | doi:10.20517/2347-8659.2018.26
    Published on: 31 Jul 2018  | Viewed:208  | Downloaded:7
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    Review| Open Access

    Immunotherapy for pediatric brain tumors

    Daniel B. Landi, Eric M. Thompson, David M. Ashley

    Immunotherapy, while effective against lymphoid cancers and some solid tumors, has shown less benefit against pediatric brain tumors. Tumor heterogeneity, a suppressive immune microenvironment, and the blood-brain barrier have the potential to diminish any immune-based approach and limit... Read more

    This article belongs to the Special Issue Immunotherapeutic Approaches for Treatment of Brain Tumors Neuroimmunol Neuroinflammation 2018;5:29. | doi:10.20517/2347-8659.2018.35
    Published on: 23 Jul 2018  | Viewed:1063  | Downloaded:87
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    Case Report| Open Access

    Streptococcus gallolyticus meningocephalitis in adults: the first case report in China

    Yue-Man Dai, Min Zhao, Hong-Ji Lu, Li-Xin Wan

    We report on the first case of a Streptococcus gallolyticus meningocephalitis in China. The bacterium was first isolated from the patient’s cerebrospinal fluid and has so far not been associated with human infections of the central nervous system. We hope our case report can give some references... Read more

    Neuroimmunol Neuroinflammation 2018;5:28. | doi:10.20517//2347-8659.2018.09
    Published on: 16 Jul 2018  | Viewed:570  | Downloaded:4
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    Review| Open Access

    Photodynamic therapy mediated immune therapy of brain tumors

    Henry Hirschberg, Kristian Berg, Qian Peng

    Photodynamic therapy of tumors requires the topical, systemic or oral administration of a photosensitizing compound,illumination of the tumor area by light of a specific wavelength and the presence of oxygen. Light activation of the photosensitizer transfers energy to molecular oxygen creating... Read more

    This article belongs to the Special Issue Immunotherapeutic Approaches for Treatment of Brain Tumors Neuroimmunol Neuroinflammation 2018;5:27. | doi:10.20517/2347-8659.2018.31
    Published on: 10 Jul 2018  | Viewed:660  | Downloaded:50
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    Technical Note| Open Access

    Classification of brain tumor using devernay sub-pixel edge detection and k-nearest neighbours methodology

    Ayush Arora, Ritesh Kumar, Shubham Tiwari, Mysore Shwetha, Selvam Venkatesan, Ramesh Babu

    Any disease can be treated only once it is imaged, detected and classified. This paper proposes a set of algorithms for classification of a brain tumor with better accuracy and efficiency. The proposal uses a JPEG format of the DICOM image fed into three stages namely pre-processing, segmentation... Read more

    This article belongs to the Special Issue Immunotherapeutic Approaches for Treatment of Brain Tumors Neuroimmunol Neuroinflammation 2018;5:26. | doi:10.20517/2347-8659.2018.11
    Published on: 19 Jun 2018  | Viewed:503  | Downloaded:20
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    Review| Open Access

    A concise review of immunotherapy for glioblastoma

    Omer Sager, Ferrat Dincoglan, Selcuk Demiral, Bora Uysal, Hakan Gamsiz, Bahar Dirican, Murat Beyzadeoglu

    Glioblastoma (GB) is the most common and aggressive form of primary brain tumors in adults with a universally poor prognosis despite multimodal management including surgery, chemotherapy and radiation therapy. Among the novel therapeutic strategies, immunotherapy deserves particular attention... Read more

    This article belongs to the Special Issue Immunotherapeutic Approaches for Treatment of Brain Tumors Neuroimmunol Neuroinflammation 2018;5:25. | doi:10.20517/2347-8659.2018.12
    Published on: 15 Jun 2018  | Viewed:498  | Downloaded:60
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    Commentary| Open Access

    Commentary on “Depression severity and its predictors among multiple sclerosis patients in Saudi Arabia: a cross-sectional study”

    Thomas Müller Neuroimmunol Neuroinflammation 2018;5:23. | doi:10.20517/2347-8659.2018.27
    Published on: 7 Jun 2018  | Viewed:316  | Downloaded:15
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    Original Article| Open Access

    Shifting paradigm in brain abscess management at tertiary care centre in Nepal

    Prakash Kafle, Mohan Raj Sharma, Sushil Krishna Shilpakar, Gopal Sedain, Amit Pradhanang, Ram Kumar Shrestha, Binod Raj Bhandari, Christine Groves

    Aim: Brain abscess is a challenging clinical entity with substantial high case fatality rates despite significant advances in imaging techniques, laboratory modalities, surgical interventions, and antimicrobial treatment.Otogenic and cardiogenic sources are among the most common. Classic clinical... Read more

    This article belongs to the Special Issue Updates on neuro-immunological and neuro-inflammatory lesions Neuroimmunol Neuroinflammation 2018;5:24. | doi:10.20517/2347-8659.2018.10
    Published on: 7 Jun 2018  | Viewed:368  | Downloaded:19
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    Commentary| Open Access

    Commentary on interactions between neurotropic pathogens, neuroinflammatory pathways, and autophagic neural cell death

    Michaela Cellina, Marcello Orsi Neuroimmunol Neuroinflammation 2018;5:22. | doi:10.20517/2347-8659.2018.15
    Published on: 5 Jun 2018  | Viewed:280  | Downloaded:17
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