fig1

Figure 1. Factors associated with the formation of cerebral aneurysms. TNF-α: tumor necrosis factor-alpha; IKK: inhibitor of kappa kinase; NF-κB: nuclear factorkappa B; MCP-1: monocyte chemoattractant protein-1; iNOS: inducible nitric oxide synthase; IL-1β: interleukin-1b; MMPs: matrix metalloproteinases; SMCs: smooth muscle cells; ECM: extracellular matrix