fig1

Isolated neurosarcoidosis presenting with recurrent hydrocephalus

Figure 1. (a and b) Outside institution T1 postcontrast magnetic resonance imaging (MRI) (5 months after initial presentation); (c‑f) T1 postcontrast MRI obtained upon admission to our institution (3.5 years after initial presentation) that demonstrates leptomeningeal enhancement throughout the central nervous system; (g and h) Intraoperative photographs of the exposed nerve roots at the L3 level of the Cauda equina; (g) Micrograph before the biopsy. The yellow‑gray, nodular, hyper‑vascular lesion intimately related to the leptomeninges that was biopsied is marked by a black stimulation probe; (h) Micrograph demonstrating the lesion after biopsy (black arrow) and two lesions (blue arrows) that produced motor potentials upon stimulation; (i) Photomicrograph depicting confluent nonnecrotizing granulomas (arrows) involving fibrocollagenous tissue of leptomeninges (arrowhead), and nerve fibers (asterisk); H and E, ×100. Inset shows one highlighted granuloma at ×400

Neuroimmunology and Neuroinflammation
ISSN 2349-6142 (Online) 2347-8659 (Print)

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Portico

All published articles are preserved here permanently:

https://www.portico.org/publishers/oae/