fig1

Figure 1. A possible neuronal network for the anterior cingulate cortex (ACC) in pain transmission. Sensory inputs from the periphery are conveyed to the dorsal root ganglion (DRG) and then to the spinal dorsal horn (SDH). Some of the SDH neurons send ascending projection to the neurons in the thalamus. Subsequently, the outputs from the thalamus synapse on the neurons in the amygdala, ACC and other cortical neurons (not shown)