• Topic: Neuroimmunology and Cancer|Open Access

    Targeting glioblastoma with oncolytic adenovirus delta 24

    Konstantinos I. Tsamis , George A. Alexiou , Athanassios P. Kyritsis
    Neuroimmunol Neuroinflammation 2015;2:1-3. | doi:10.4103/2347-8659.149392
    Published on: 15 Jan 2015  | Viewed:3808  | Downloaded:110
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  • Topic: Neuroimmunology and Cancer|Open Access

    Integrins and focal adhesion kinase in the malignant behavior of gliomas

    Efstathia Giannopoulou , Andreas Tzakos , Andreas A. Argyriou
    Glioblastoma multiforme (GBM) is the most common type of glioma and is associated with a very poor prognosis. The standard treatment includes radiotherapy concurrent with temozolomide, however recently the Food and Drug Administration approved bevacizumab for use in patients with progressive... Read more
    Neuroimmunol Neuroinflammation 2015;2:4-7. | doi:10.4103/2347-8659.149395
    Published on: 15 Jan 2015  | Viewed:3367  | Downloaded:133
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  • Topic: Neuroimmunology and Cancer|Open Access

    A potential role of karyopherin a2 in the impaired maturation of dendritic cells observed in glioblastoma patients

    Konstantinos Gousias , Alexander von Ruecker , Gerrit H. Gielen , Pitt Niehusmann , Andreas Waha , Hartmut Vatter , Matthias Simon
    Aim: Patients with glioblastomas demonstrate well-documented immunological impairments including decreased numbers of mature dendritic cells (DCs). Recent data identified karyopherin a2 (KPNA2), a nucleocytoplasmic shuttling receptor, as diagnostic and prognostic biomarker for gliomas. The aim of... Read more
    Neuroimmunol Neuroinflammation 2015;2:8-14. | doi:10.4103/2347-8659.149396
    Published on: 15 Jan 2015  | Viewed:6740  | Downloaded:104
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  • Topic: Neuroimmunology and Cancer|Open Access

    Serum IgE levels in patients with intracranial tumors

    George A Alexiou , Amalia Kallinteri , Eleni Nita , Panagiota Zagorianakou , Stamatina Levidiotou , Spyridon Voulgaris
    Aim: Several epidemiological studies have shown an inverse correlation between allergy and brain cancer. The purpose of this study was to compare the serum IgE levels between patients with gliomas and nonglial tumors and their possible prognostic role. Methods: A total of 84 patients with... Read more
    Neuroimmunol Neuroinflammation 2015;2:15-7. | doi:10.4103/2347-8659.149398
    Published on: 15 Jan 2015  | Viewed:5514  | Downloaded:125
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  • Topic: Neuroimmunology and Cancer|Open Access

    The influence of postoperative infection in survival of patients with high-grade gliomas

    George A Alexiou , Amalia Kallinteri , Euaggelos Michos , Panagiota Zagorianakou , Efthalia Priavali , Dimitrios Pachatouridis , Stamatina Levidiotou , Spyridon Voulgaris
    High-grade gliomas are the most common type of brain tumors. Of these, glioblastoma account for 60-70% and despite treatment carries a dismal prognosis. Postoperative surgical site infection has been associated with prolonged survival. Herewith, we present a case of glioblastoma and a case of... Read more
    Neuroimmunol Neuroinflammation 2015;2:18-20. | doi:10.4103/2347-8659.149418
    Published on: 15 Jan 2015  | Viewed:4427  | Downloaded:159
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  • Original Article|Open Access

    Cardiac autonomic function in patients with myasthenia gravis: analysis of the heart-rate variability in the time-domain

    Sherifa Ahmed Hamed , Khaled Osama Mohamad , Mohamad Adam
    Aim: Myasthenia gravis (MG) is a neuromuscular transmission disorder caused by acetylcholine receptor autoantibodies. Cardiac autonomic dysfunctions were rarely reported in patients with MG. Functional cardiac abnormalities were variable and reported in patients at severe stages of the disease... Read more
    Neuroimmunol Neuroinflammation 2015;2:21-5. | doi:10.4103/2347-8659.149419
    Published on: 15 Jan 2015  | Viewed:7380  | Downloaded:132
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  • Original Article|Open Access

    Central somatosensory conduction slowing in adults with isolated elevated plasma level of homocysteine

    Jin Jun Luo , Favio Bumanlag , Ramin Ansari , Ya-Mei Tang , Nae J. Dun
    Aim: Elevated plasma level of homocysteine (eHcy) is a recognized risk factor for dementia. However, whether the central conduction is affected in patients with an isolated eHcy is unknown. In this study, we addressed whether central conduction is altered in adults with eHcy. Methods: Evoked... Read more
    Neuroimmunol Neuroinflammation 2015;2:26-30. | doi:10.4103/2347-8659.149420
    Published on: 15 Jan 2015  | Viewed:6121  | Downloaded:114
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  • Original Article|Open Access

    Influence of chlorpyrifos oxon on the development and progression of Alzheimer's disease in amyloid precursor protein transgenic mice

    Jin Yu , Hong Zhu , Aruna Bhat , Hanaa El-Sayed , Tatyana Gudz , Sebastiano Gattoni-Celli , Mark S. Kindy
    Aim: Alzheimer's disease (AD) is a devastating neurological disorder and the most common form of dementia. Until date, the cause of AD eludes us, but a number of hypotheses have been put forward to try and understand the mechanisms involved. A series of studies have indicated that environmental... Read more
    Neuroimmunol Neuroinflammation 2015;2:31-42. | doi:10.4103/2347-8659.149421
    Published on: 15 Jan 2015  | Viewed:5130  | Downloaded:87
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  • Case Report|Open Access

    Cardiac arrhythmia with premature ventricular contractures induced by interferon beta in a patient with multiple sclerosis

    Igor Sobol , Marina Sobol , Konstantin E. Balashov
    Multiple sclerosis (MS) is an immune-mediated inflammatory and neurodegenerative disease of the central nervous system. Interferon (IFN) beta is an active ingredient of five out of twelve disease modifying treatments approved for MS. We report a case of IFN-beta-induced cardiac arrhythmia with... Read more
    Neuroimmunol Neuroinflammation 2015;2:43-5. | doi:10.4103/2347-8659.149422
    Published on: 15 Jan 2015  | Viewed:4266  | Downloaded:117
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  • Case Report|Open Access

    Multiple autoimmune antibody limbic encephalitis: a case in a pregnant woman

    Meha Goyal , Kasey L. Gildersleeve , Stuart L. Tomko , Joseph S. Kass
    Autoimmune limbic encephalitis is most commonly associated with antibodies against the N-methyl-D-aspartate receptor (NMDAR), among other neuronal cell surface receptors. Here, a case of a pregnant female with limbic encephalitis in the presence of multiple additional autoimmune antibodies is... Read more
    Neuroimmunol Neuroinflammation 2015;2:46-8. | doi:10.4103/2347-8659.149423
    Published on: 15 Jan 2015  | Viewed:4097  | Downloaded:122
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Neuroimmunology and Neuroinflammation Print ISSN: 2347-8659; Online ISSN: 2349-6142
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