fig1

Figure 1. Flowchart summarizing a preferred diagnostic approach to AIE. AIE: anti-neuronal autoimmune encephalitis; CSF: cerebrospinal fluid; CBA: cell-based assay; EEG: electroencephalogram; TBA: tissue-based assays; CT: computed tomography; PET: positron emission tomography; MRI: magnetic resonance imaging; IVIG: intravenous immunoglobulin; PLEX: plasmapheresis